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Larger Image Fig. 5. Expression pattern of pancreatic genes. Embryos at three stages were examined by in situ hybridization using specific probes for each clone. CEL was expressed in dorsal and ventral pancreas rudiments (arrowhead) at stage 40 and continued after stage 42 (A,B,C: stages 40, 42 and 44, respectively). PE2 (D,E,F: stages 40, 42 and 44, respectively), PDIp (J,K,L: stages 40, 42 and 44, respectively) and DNaseI (M,N,O: stages 40, 42 and 44, respectively) were detected as weak signals at stage 40 and strong signals at stage 42. PP11 (G,H,I: stages 40, 42 and 44, respectively) was barely detectable at stage 40 but expression increased by stage 42. Image published in: Sogame A et al. (2003) Copyright © 2003. Image reproduced with permission of the Publisher, John Wiley & Sons.
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