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FIG. 5. Correlations with flanking GC content. (A) Flanking GC content exhibits greater correlation with GC3 (genic GC at third codon positions) in human and chicken (higher r2) than in Anolis. (B) Flanking GC content correlate between human and chicken, implying conserved isochore structure in mammals and birds, but less so between Anolis and human or chicken. Sample sizes (N) include genes with long open-reading frame (length > 1,000 bp) that were not saturated (dS < 1) or undergoing positive selection (dN/dS < 1). Image published in: Fujita MK et al. (2011) The Author(s) 2011. Creative Commons Attribution-NonCommercial license Larger Image Printer Friendly View

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