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Figure 4. Long-term developmental exposure to TNF-α does not alter intrinsic membrane currents of tectal neurons. (A) Family of current traces recorded in response to a series of depolarizing steps from -60 to +30 mV. The fast inward current is a voltage-gated Na+ current while the outward current is a voltage-gated K+ current. (B) I-V curves for Na+ and K+ currents in control tectal cells and cells from TNF-α reared tadpoles. (C) Maximum peak amplitudes of Na+ and K+ currents from both groups show no significant differences. For P-values see Results. N.S., not significant. Image published in: Lee RH et al. (2010) Copyright ©2010 Lee et al; licensee BioMed Central Ltd. Creative Commons Attribution license Larger Image Printer Friendly View

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