Xenbase Image ID: 121314

Figure 7. . The MWC-based four-plus-two-conformation model for InsP3R channel gating. Only conformation transitions are represented in the schemes. Reactions involving binding of InsP3 and Ca2+ to the InsP3R channel and the state of occupation of the various ligand-binding sites of the channel are omitted from the schemes for clarity. The green boxes represent the grouping of the open A* and closed A′ conformations into the active A conformation, and the grouping of the C* and C′ conformations into the active C conformation. Image published in: Mak DO et al. (2003) Copyright © 2003, The Rockefeller University Press. Creative Commons Attribution-NonCommercial-ShareAlike license Larger Image Printer Friendly View

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