XB-IMG-119901
Xenbase Image ID: 119901
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Figure 2. Ca2+-dependent inactivation of Ca2+ current in the cloned cardiac Ca2+ channel α1Cβ2a. Superimposed traces evoked in an oocyte expressing α1C and β2a subunits, and the effect of DHP agonist Bay K 8644 (â). The voltage protocol was the same as in Fig. 1. (A) Voltage steps from HP â90 mV; Ba2+ was the charge carrier (10 mM Ba2+). (B) Currents recorded in 5 mM Ca2+. (C) Same voltage steps as in A, Ba2+ currents recorded in the presence of 50 nM Bay K 8644 (â). (D) Same voltage steps as in B, Ca2+ currents recorded in the presence of Bay K 8644 (â). Linear components were digitally subtracted by subpulses from the holding potential using the P/â4 method. Image published in: Noceti F et al. (1998) Image reproduced on Xenbase with permission of the publisher and the copyright holder. Creative Commons Attribution-NonCommercial-ShareAlike license Larger Image Printer Friendly View |