Xenbase Image ID: 124288

Figure 4. Wnt9b is required for the elongation and narrowing of kidney tubulesRepresentative sections through wild type DBA positive tubules from E13.5 (a), E15.5 (b), E17.5 (c), and P1 mice (d) showing the number of nuclei composing the wall of the tubule. Outlined tubules represent transverse sections. Quantitation reveals that the number of cells within the wall of wild-type collecting duct (black bars in e, n=563, 606, 844, and 692 for E13.5, 15.5, 17.5 and P1 respectively) and proximal tubules (black bars in f, n=425, 1030, 791, and 778 for E13.5, 15.5, 17.5 and P1 respectively) significantly decreases during the embryonic period. The number of cells within the tubule wall is significantly increased in Wnt9b mutant kidneys (white bars in e and f, n=384 or 412, 521 or 424, 915 or 902, and 665 or 635 for DBA or LTL at E13.5, 15.5 17.5 or P1 respectively). N=3 kidneys for each stage, tubular segment and genotype. Error bars represent standard error of the mean. Image published in: Karner CM et al. (2009) Image downloaded from an Open Access article in PubMed Central. Image reproduced on Xenbase with permission of the publisher and the copyright holder. Larger Image Printer Friendly View

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