Xenbase Image ID: 124120

Figure 8. Effects of activating and repressing regulatory factors on endogenous and introduced promoter DNA in somatic cells and germ cells.Silencing factors are red/black while activating factors are green. Solid lines show paths of function while dashed lines indicate either absence or failure to function. (A) Silencing factors do not repress an introduced germ cell gene promoter in somatic cells, allowing activating factors to (inappropriately) drive transcription. (B) Silencing factors are absent or do not function on endogenous and introduced promoters in germ cells, while activating factors result in transcription from both types of DNA. Image published in: Li D et al. (2009) Li et al. Creative Commons Attribution license Larger Image Printer Friendly View

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