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Figure 3. Synaptic stimulation during somatic action potentials induces a post-burst ADP.(A) Synaptic stimulation (SYN) was paired with somatic action potentials (AP) to evoke the post-burst ADP. Stimuli were 100 Hz five action potentials only, 50 Hz for 1 s of synaptic stimulation only, or both stimuli combined together. Examples for each condition from a single cell are overlaid on the right. (B) Time course of the change in post-burst potential in control and group I mGluR receptor antagonists. Representative average responses were obtained from three consecutive traces in control and MPEP/LY. Arrows indicate the amplitude of the change in post-burst potentials. The baseline membrane potential is indicated by dotted lines. (C) Normalized change in post-burst potential in control and MPEP/LY (n = 5 cells in each condition; results for each cell are shown by the lightly colored lines). Image published in: Park JY et al. (2010) Park et al. Creative Commons Attribution license Larger Image Printer Friendly View

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