Xenbase Image ID: 122425

Figure 2. . Inhibition of mutant E166A by CPA. Patch-clamp data from a representative inside-out patch are shown in the absence of CPA (A), and in the presence of 0.1 mM CPA (B) and 5 mM CPA (C). The pulse protocol consists of a prepulse to 80 mV, a test pulse to various potentials (the responses to −140, −100, −60, −20, 20, 60, and 100 mV are shown) and a “tail” pulse to 80 mV. The chemical structure of CPA is shown in C as an inset. Nearly identical results were obtained for the mutation E166S (not depicted). Image published in: Traverso S et al. (2003) Copyright © 2003, The Rockefeller University Press. Creative Commons Attribution-NonCommercial-ShareAlike license Larger Image Printer Friendly View

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