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Figure 14. Voltage and extracellular Na+ dependence of GAT1 charge movements in whole-oocyte voltage clamp. The simulations are calibrated as elementary charges (e) moved through membrane field per single transporter. The results are from Mager et al. 1996. (A) Voltage dependence of charge moved at 96 (♦), 77 (□), 48 (▪), 24 (○), and 12 (•) mM extracellular Na+. (B) Na+i dependence of charge moved at −80 mV by application of 96 mM extracellular Na+.

Image published in: Hilgemann DW and Lu CC (1999)

© 1999 The Rockefeller University Press. Creative Commons Attribution-NonCommercial-ShareAlike license

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