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Figure 7. PGO effect and pH-dependency in hMCT4 mutants.(A) Uptake of 0.1 mM L-lactate was measured before and after treatment with 100 mM PGO in oocytes injected with hMCT4-WT or the indicated mutants. Data are presented as means ± S.E. of three – five experiments. (B) Uptake of L-lactate was measured in hMCT4-WT or -R198Q expressing oocytes with 10 min incubation in transport buffer of pH 5.5 or pH 7.5 in the presence of 0.1 mM L-lactate. Data are presented as means ± S.E. of four – five experiments. Image published in: Sasaki S et al. (2013) Image reproduced on Xenbase with permission of the publisher and the copyright holder. Creative Commons Attribution license Larger Image Printer Friendly View

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