Xenbase Image ID: 125122

Figure 2. A variant CRE binding site is required for activity-dependent transcriptional regulationa, a control construct in which 384 bp of the tlx3 promoter drives firefly luciferase reports an increase in relative luminescence (RL) when coinjected with Kir and a decrease in RL when coinjected with Nav. b, mutating the AP1 site (red) has no effect on luciferase expression. c, mutating the CRE site (red) eliminates the activity-dependence of luciferase expression. b–d, data are mean±SEM; n≥3 clutches; *, P<0.05. Image published in: Marek KW et al. (2010) Image downloaded from an Open Access article in PubMed Central. Image reproduced on Xenbase with permission of the publisher and the copyright holder. Larger Image Printer Friendly View

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