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Figure 8. . Relationship of permeability changes to steady-state currents, I1 and I2. (A) The relationship between I1 amplitude and I2 PNMDG+/PNa+. (B) The relationship between I1 PNMDG+/PNa+ and I2 PNMDG+/PNa+. (C) The relationship between I2 amplitude and I2 PNMDG+/PNa+; the two parameters are well correlated (r = 0.9). We verified that slope conductance values followed a similar trend to current peak amplitudes for the majority of mutants where such data was available. For this figure, the single point mutants shown in Fig. 6 have been pooled, and there is no point for the r414m chimers because there was no measurable I2.

Image published in: Eickhorst AN et al. (2002)

Copyright © 2002, The Rockefeller University Press. Creative Commons Attribution-NonCommercial-ShareAlike license

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