Xenbase Image ID: 144486

FIGURE 3. SCP3 is required for the expression of Nodal/Activin and BMP target genes during early Xenopus embryogenesis. (A) Oocytes were injected with 20 or 40 ng of scp3 MO-1. After the maturation, host-transfer and fertilization, the embryos were collected at stage 9.5, 10 and 10.5 for qPCR. NC, negative control, uninjected embryos treated the same as injected ones. (B) Two-cell stage embryos were injected with 60 ng of std MO or scp3 MO-1, and analyzed at stage 10.5 using in situ hybridization for the indicated genes. Image published in: Sun G et al. (2015) Copyright © 2015. Image reproduced with permission of the Publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue a2m.S A2Moo, Alpha2-macroglobulin, edd, endod, endodermin, LOC108695707, ovomacroglobulin X. laevis Throughout NF stage 10.5 upper blastopore lip dorsal marginal zone tbxt.S bra, brachyury, ntl, t, t-a, t-b, X-bra, Xbra, Xbrachyury X. laevis Throughout NF stage 10.5 mesoderm marginal zone chrd.S chd, chordin, chrd.1, LOC108716939, X-chordin X. laevis Throughout NF stage 10.5 upper blastopore lip involuted dorsal mesoderm ventx1.L posterior-ventral 1, PV.1, ventx1.1, ventx1.1-a, ventx1.1-b, Xvent-1b X. laevis Throughout NF stage 10.5 marginal zone ventral marginal zone ventro-lateral marginal zone dorso-lateral marginal zone lhx5.S xlim-2a, xlim-5, Xlim5 X. laevis Throughout NF stage 10.5 ectoderm Image source: Published Experiment + Assay Source Phenotypes and Disease Xla Wt + ctdspl MO + NF10.5 (morphology) fig.3.b Expression Phenotype decreased amount a2m.S expression in blastopore lip decreased amount chrd.1.S expression in dorsal marginal zone decreased amount tbxt.L expression in marginal zone decreased amount ventx1.2.S expression in marginal zone Larger Image Printer Friendly View

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