Xenbase Image ID: 49105

Fig. 2. PAR-1 promotes neurite differentiation in superficial layer progeny. (A) Control-grafted stage 25 Xenopus embryos showing that labelled cells lack neurites. (B) Lineage-labelled cells from PAR-1TA-expressing superficial layer grafts at stage 25 showing numerous cells bearing long neurite-like processes (arrows). (C) Quantification of superficial layer graft progeny showing significant induction of differentiation in PAR-1TA-expressing, but not control-grafted, embryos. Neurite-like processes were scored conservatively as labelled cell extensions that extended at least 5 μm from the cell body. *, P=0.025; Student's t-test. Image published in: Tabler JM et al. (2010) Copyright © 2010. Image reproduced with permission of the Publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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