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Figure 3. (a) A representative recording from patch-clamp experiment showing camphor-induced mTRPV3 activity inhibited by 100 nM icilin (61% inhibition; n = 6). HEK293 cells expressing mTRPV3 were held at –40 mV holding potential at ~33°C. (b) A representative recording from patch-clamp experiment showing 2-APB-induced mTRPV3 activity inhibited by 100 nM icilin (68% inhibition; n = 7) under similar conditions as above. (c) A representative recording from patch-clamp experiment showing icilin-dependent (100 nM) inhibition of mTRPV3 activity induced by both camphor and 2-APB (74% inhibition; n = 7) under similar conditions as above.

Image published in: Sherkheli MA et al. (2012)

Copyright © 2012 Muhammad Azhar Sherkheli et al. Creative Commons Attribution license

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