XB-IMG-120872
Xenbase Image ID: 120872
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Figure 6. Monoamine unblock kinetics are strongly dependent on alkyl chain length. (A) Kir2.1 currents recorded from an inside-out membrane patch in response to voltage steps to potentials between 0 and −150 mV after a prepulse to +50 mV, from a holding potential of 0 mV as indicated. In each case, the control recordings were obtained after removal of rectification after patch excision, and the patch was then exposed to 100 μM monoamines as indicated. Scale bars: 2 nA and 5 ms. (B) Time constant of unblock (τOff) obtained from exponential fits (see text) to currents like those shown in A plotted versus membrane potential (Vm). Image published in: Pearson WL and Nichols CG (1998) Image reproduced on Xenbase with permission of the publisher and the copyright holder. Creative Commons Attribution-NonCommercial-ShareAlike license Larger Image Printer Friendly View |