Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-IMG-120872

Xenbase Image ID: 120872


Figure 6. Monoamine unblock kinetics are strongly dependent on alkyl chain length. (A) Kir2.1 currents recorded from an inside-out membrane patch in response to voltage steps to potentials between 0 and −150 mV after a prepulse to +50 mV, from a holding potential of 0 mV as indicated. In each case, the control recordings were obtained after removal of rectification after patch excision, and the patch was then exposed to 100 μM monoamines as indicated. Scale bars: 2 nA and 5 ms. (B) Time constant of unblock (τOff) obtained from exponential fits (see text) to currents like those shown in A plotted versus membrane potential (Vm).

Image published in: Pearson WL and Nichols CG (1998)

Image reproduced on Xenbase with permission of the publisher and the copyright holder. Creative Commons Attribution-NonCommercial-ShareAlike license

Larger Image
Printer Friendly View

Return to previous page