Xenbase Image ID: 120648

Figure 6. Pore properties of voltage-insensitive 124Q channels. (A) Unidirectional single channel currents measured at +40 mV (Tris Ringer//“X+” EGTA, shaded histograms) and at −40 mV (“X+” Ringer//Tris EGTA, open histograms). The histograms show the following permeability sequence: K+ > Rb+ > NH4+ > Cs+ and Na+. (B) 124Q channels are sensitive to block by 4-AP. I–V data points from one representative oocyte using two-electrode voltage clamp. Macroscopic current seen in 115-mM external K+ solution (▴) appears effectively blocked after addition of 10 mM 4-AP to the bath solution (○). Image published in: Bao H et al. (1999) Image reproduced on Xenbase with permission of the publisher and the copyright holder. Creative Commons Attribution-NonCommercial-ShareAlike license Larger Image Printer Friendly View

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