Xenbase Image ID: 121272

Figure 2. . Comparison of macroscopic currents through wild-type and mutant Kir2.1 expressed in Xenopus oocytes. (A) Macroscopic currents recorded using two-electrode voltage clamp with Xenopus oocytes expressing wild-type Kir2.1 or S165L, D172N, D172N, & S165L double mutant, D172N & E224G & E299S triple mutant, or triple mutant & S165L. Representative current traces recorded in 10 mM K+o. The holding potential was −50 mV; step pulses from 50 to −160 mV were applied in 10-mV decrements. (B) I-V relationships for the data in A; values were measured 50 ms after the onset each step pulse. (C) Conductance-voltage (G-V) relationship for the data in B. Image published in: Fujiwara Y and Kubo Y (2002) Copyright © 2002, The Rockefeller University Press. Creative Commons Attribution-NonCommercial-ShareAlike license Larger Image Printer Friendly View

Return to previous page