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Fig. 5. Reprogramming signal strength and efficiency are optimal between 100 and 300 nuclei. Transcription of Sox2 from different numbers of C2C12 nuclei injected into Xenopus oocytes and maintained at 16 °C for 48 h (a). Efficiency (absolute number of transcripts/transplanted nucleus) of Sox2 reactivation from different numbers of C2C12 nuclei injected into Xenopus oocytes and cultured at 16 °C for 48 h (b). P < 0.02, error bars are mean SD.

Image published in: Halley-Stott RP et al. (2010)

© 2010 Elsevier Inc. Creative Commons Attribution license

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