Xenbase Image ID: 122353

Figure 10. . Model for COOH-terminal region in the resting and activating configurations. Cartoons of HCN2 COOH-terminal region from the side view, both in the resting configuration (left) and the active configuration (right). COOH-terminal regions of two subunits (dark and light gray) are shown below the membrane-spanning portion of the channel. α helices are shown with narrow cylinders, and the β rolls of the CNBDs are shown with wide cylinders. Salt bridge residues are shown: the positive B' helix residue (plus sign within a square) and the two negative residues on the D' helix and the β roll (minus signs within a circle or square, respectively). Image published in: Craven KB and Zagotta WN (2004) Copyright © 2004, The Rockefeller University Press. Creative Commons Attribution-NonCommercial-ShareAlike license Larger Image Printer Friendly View

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