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Fig. 1. Dynamic exclusion allows the mass spectrometer to more efficiently identify peptides in a sample. The first scan measures the ions with the highest intensity (most abundant). These masses are added to a temporary ‘exclusion’ list for a period of typically 30–90 s. Once the high intensity peaks have been sequenced and excluded the MS can measure peaks under the threshold, thereby detecting less abundant peptides.

Image published in: Hodge K et al. (2013)

© 2013 Elsevier B. Creative Commons Attribution license

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