XB-IMG-116323
Xenbase Image ID: 116323
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Figure 3. Effects of tyrosine kinase inhibitor and dominant-negative RAS antibody on IGF-1 effects on the serotonin response in Xenopus oocytes. Shown are peak Cl- currents in response to 5-HT after the indicated treatments. (A) Genistein, a tyrosine kinase inhibitor, blocks the inhibitory effect of IGF-1 on the 5-HT response. The data are presented as mean ± S.E.M. of 11-12 oocytes (*, P < 0.05). (B) RAS antibody, Y13-259, blocks the inhibitory effect of IGF-1 on the 5-HT response. The data are presented as mean ± S.E.M. of 6 oocytes (*, P < 0.05). Image published in: Hurley JH et al. (2003) Image downloaded from an Open Access article in PubMed Central. Copyright © 2003 Hurley et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL. Larger Image Printer Friendly View |