Xenbase Image ID: 121287

Figure 3. . The β1 subunit had little effect on burst duration and Po of Slo1 core/Slo3 tail channels at 30 mV, while decreasing the voltage sensitivity. (A and B) Representative single-channel currents recorded from Slo1core/Slo3 tail channels with and without β1 subunits, for 0, 20, and 100 μM Ca2+i at 30 mV. (C and D) Representative macrocurrents recorded with and without β1 subunits, for either 0 or 20 μM Ca2+i. Currents were held at −100 mV and then activated by stepping to potentials between −50 to 200 mV in increments of 10 mV, with tail currents measured at −80 mV. (E) G-V curves derived from tail currents of Slo1core/Slo3 tail channels with and without β1 subunits. The average voltage sensitivity was 22.6 ± 0.4 mV/e-fold without β1 subunits and 28.8 ± 0.5 mV/e-fold with β1 subunits. (F) Plots of V0.5 for Slo1 core/Slo3 tail channels with and without β1 subunits. Image published in: Qian X et al. (2002) Copyright © 2002, The Rockefeller University Press. Creative Commons Attribution-NonCommercial-ShareAlike license Larger Image Printer Friendly View

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