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Figure 8. Cav2.3 knockout mice exhibit a reduced DHPG-induced medium ADP compared to wild-type mice.(A) Examples of responses in control (black) and following application of 10 µM effect of DHPG (red, blue) in wild-type (WT) and Cav2.3 knockout (KO) mice. Stimulus is five brief current stimuli (as in Figure 1E). Action potentials are truncated. (B) Time course of effects of DHPG in WT (red) and Cav2.3 KO (blue) mice. Interval between trials is 20 s. (C) Summary of effects of DHPG on medium ADP in WT (red) and Cav2.3 KO (blue) mice. Unpaired t test: ** p<0.001. Image published in: Park JY et al. (2010) Park et al. Creative Commons Attribution license Larger Image Printer Friendly View

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