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Figure 4. The sensitivity of MCT1/2 and MCT2/1 chimaeras to inhibition by AR-C155858(A) Immunofluorescence confocal microscopy data with appropriate C-terminal antibodies (Ab) of sections of oocytes expressing MCT1/2 or MCT2/1 with or without exogenous embigin. (B) Inhibition of lactate transport activity by increasing concentrations of AR-C155858 determined using 0.5 mM L-[14C]lactate (pH 6) over 10 min. Results are means±S.E.M. for ten separate oocytes at each inhibitor concentration.

Image published in: Ovens MJ et al. (2010)

© 2010 The Author(s) The author(s) has paid for this article to be freely available under the terms of the Creative Commons Attribution Non-Commercial Licence (http://creativecommons. Creative Commons Attribution-NonCommercial license

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