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XB-IMG-127654

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Figure 3. Complete seven-state model used to simulate SGLT1 transient and steady-state currents. Intracellular binding of Na+ and αMG have been lumped into a single transition (k17). The scheme includes a five-state model (gray box) which is the simplest structure leading to an accurate fit of the transient currents in the absence of αMG. The different states suggested by the LeuT structural family are labeled S1 to S8 and are presented above and below the kinetic model.

Image published in: Longpré JP et al. (2012)

© 2012 Longpré et al. Creative Commons Attribution-NonCommercial-ShareAlike license

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