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XB-IMG-119142

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Figure 4. Models. (A) Molecular architecture of condensin and cohesin. N and C indicate NH2-terminal and COOH-terminal nonhelical domains, respectively, of the SMC subunits. By analogy to BsSMC, we assume here that the coiled-coil arms of the eukaryotic SMC heterodimers are arranged into an antiparallel fashion. The relative positions of the non-SMC subunits (shown in yellow) are arbitrary. (B) Hypothetical models of the interactions of condensin (left) and cohesin (right) with DNA.

Image published in: Anderson DE et al. (2002)

Copyright © 2002, The Rockefeller University Press. Creative Commons Attribution-NonCommercial-ShareAlike license

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