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Fig. 7. Effects of the extracellular PH on the dose-responsiveness of propafenone on fkv1.4ΔN channel at extracellular potassium concentration of 98 mM[K+]0, 5 mM[K+]0, and 1 mM[K+]0. Xenopus oocytes with all covering tissues. The PH value of the extracellular solution was changed by PH 6 (triangles) and PH 7.4 (squares) and PH 8 (diamonds). Graphical evaluations under propafenone concentrations of 10 µM/L up to 1,000 µM/L. The graphical evaluation shows the fraction of inhibition of the fkv1.4ΔN currents. All values represents means±SEM of the five experiments each (I current, U voltage). Image published in: Wang Z et al. (2009) Copyright © 2009 The Korean Academy of Medical Sciences. Creative Commons Attribution-NonCommercial license Larger Image Printer Friendly View

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