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Figure 6. Comparison of binding to 1 by Aurora B, Aurora A, and ABL2. (A) Aurora B:1. (B) Aurora A:1 (PDB ID: 3E5A).13 (C) ABL2:1 (PDB ID: 2XYN).25 (D) Overlay of the DFG motifs of the complexes with 1 of Aurora B (in yellow) and Aurora A (in pink). (E) Overlay of the DFG motifs of the complexes with 1 of Aurora B (in yellow) and ABL2 (in blue).

Image published in: Elkins JM et al. (2012)

Image downloaded from an Open Access article in PubMed Central. Copyright © 2012 American Chemical Society

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