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Figure 6. In situ hybridization analysis of Notch1, 2, 3, Serrate1, and lunatic fringe expression in the mandibular incisor of 2-d-old mice. (a–a′′) Notch1 is expressed in stellate reticulum in cervical loop (a) and in stratum intermedium and stellate reticulum in the zone of cell differentiation (a′′). (b–b′′) Notch2 is expressed in outer enamel epithelium and stellate reticulum in cervical loop (b) and in stratum intermedium and stellate reticulum in the zone of cell differentiation (b′′). (c–c′′) Notch3 is absent from the cervical loop (c), but is expressed in stellate reticulum and in the zone of cell differentiation (c′′). (d–d′′) Serrate1 is absent from the cervical loop (d), but is expressed in ameloblasts (d′′). (e-e′′) Lunatic fringe is expressed in basal epithelium in cervical loop continuing in the inner enamel epithelium (e′), and is downregulated in differentiated ameloblasts (e′′). Bar, 1 mm (χ). Bar, 200 μm (χ′ and χ′′).

Image published in: Harada H et al. (1999)

© 1999 The Rockefeller University Press. Creative Commons Attribution-NonCommercial-ShareAlike license

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