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Figure 3. Ethanol-induced conditioned place preference in ρ1 (−/−) mice.Data represent the percent of time spent on different types of floor (A, B) or on the grid floor (C, D). A. Males (n = 13–15 per genotype; F1,52 = 14, p<0.001, main effect of floor). B. Females (n = 6 per genotype; F1,20 = 5.7, p<0.05, main effect of floor; F1,20 = 13.7, p<0.01, genotype x floor interaction, *p<0.05 vs. another genotype on the same type of floor). C. Males, 1st Preference test (n = 13–15 per genotype and treatment; F1,52 = 43, p<0.001, main effect of treatment, ***p<0.001 vs. saline group of corresponding genotype). D. 2nd Preference test (Extinction). Values represent mean ± S.E.M. Data were analyzed by two-way ANOVA with Bonferroni post hoc test. ρ1 (−/−) = ρ1 null mice; (+/+) = wild type mice; EtOH = ethanol. Image published in: Blednov YA et al. (2014) Image reproduced on Xenbase with permission of the publisher and the copyright holder. Creative Commons Attribution license Larger Image Printer Friendly View |