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Figure 2. Response profiles of ORNs to amino acid and peptide stimulation.(A) Relative number of amino acid-sensitive ORNs reacting to individual amino acids (200 µM) or at least to one of the thirteen tested peptides. Only a fraction of amino acid-responsive ORNs also responded to group I peptides (1 mM, 12 of 42 ORNs in four slices) or group II peptides (200 µM, 6 of 28 ORNs in four slices). The fraction of ORNs sensitive to group I peptides did not differ from the fraction of ORNs sensitive to group II peptides. (B) Response matrix of all peptide-sensitive ORNs to the applied stimuli (green, response to applied stimulus; red, no response; grey, not tested; applied peptide concentration: ORN #1–#12, 1 mM; ORN #13–#21, 5 mM; ORN #22–#24, 10 mM; ORN #25–#31, 200 µM). [AA mix: amino acid mixture, AA: amino acids, Arg: L-arginine, Met: L-methionine, Lys: L-lysine, Gly: glycine, Pep I: group I peptides, Pep II: group II peptides]. Image published in: Hassenklöver T et al. (2012) Image reproduced on Xenbase with permission of the publisher and the copyright holder. Creative Commons Attribution license Larger Image Printer Friendly View

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