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Figure 11. Opening and closing rate constants in D2O. Opening (A) and closing (B) rate constants were determined as in Fig. 6. Since slightly different solutions were employed in these experiments (see Materials and methods), the rate constants in H2O represent the values obtained from the same patches in which we tested the effect of D2O. (C) The ratio of the opening rate constants at pH/pD 8.3 in H2O and D2O. (D) The ratio of the closing rate constants at pH/pD 8.3 in H2O and D2O. Image published in: Zifarelli G et al. (2008) © 2008 Zifarelli et al. Creative Commons Attribution-NonCommercial-ShareAlike license Larger Image Printer Friendly View

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