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Figure 10. . Effects of intracellular pH on the I-V curves of wild-type and mutant IRK1 channels. (A and B) I-V curves of wild-type and D172N mutant IRK1 channels at various intracellular pH, determined from the current records, as shown (and including those) in Fig. 9, except for those at pH 7.6, which were taken from those as shown in Fig. 4 A. (C and D) Currents through IRK1 and D172N channels, normalized to those at pH 8.5, are plotted against membrane voltage. All data points are mean ± SEM (n = 5).

Image published in: Guo D and Lu Z (2002)

Copyright © 2002, The Rockefeller University Press. Creative Commons Attribution-NonCommercial-ShareAlike license

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