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Figure 4. The effect of substitution of Na+ with organic cations on the I-V relationship of 5-HT3 receptors at saturating concentrations of 5-HT (50 µM). (Top) 5-HT3A WT receptors. (Bottom) Chimeric 5-HT3A–glvM3M4 receptors. Data points at each potential sample are plotted as the mean normalized current ± SEM along with the interpolated fit through the points. The data were normalized for clarity to the current at either +31 or +37 mV, dependent on the exact protocol used.

Image published in: McKinnon NK et al. (2011)

© 2011 McKinnon et al. Creative Commons Attribution-NonCommercial-ShareAlike license

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