Xenbase Image ID: 123641

Figure 7. Model of Force Transmission in Kv ChannelsShown is a complete monomeric subunit of the paddle chimera (PDB ID: 2R9R) and the pore region only from the adjacent subunit with which the S1–pore interface is formed. Components of the voltage sensor that are mobile along the transmembrane axis are shown in red, and components that are static along the transmembrane axis are shown in blue. The pore regions are shown in gray. The side chains of the residues forming the S1–pore interface are shown in blue ball and stick rendition, and the potassium ions lining the filter region are shown as cyan spheres. The blue arrow denotes the location of the S1–pore interface with respect to the entire protein structure. The red arrows indicate the putative direction of force transmission from the voltage sensor onto the S4-S5 linker and from the S4-S5 linker to the pore. Image published in: Lee SY et al. (2009) Copyright: © 2009 Lee et al. Creative Commons Attribution license Larger Image Printer Friendly View

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