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Figure 5. Unitary conductance of wild-type and KCNKΔ299-1001 channels is the same. Single channels were studied during open bursts in on-cell patches with 140 mM KCl solution at the indicated voltages. Open (O) and closed (C) state levels are indicated. Data were filtered at 2 kHz and sampled at 20 kHz. (A) Sample recording of a single wild-type KCNKØ channel at four indicated voltages. (B) Sample recording of a single KCNKΔ299-1001 channel as in A. (C) Current–voltage relationships of the channels in A (•) and B (○). The line is a linear fit to the data; slope conductances were indistinguishable (see results for values).

Image published in: Zilberberg N et al. (2000)

© 2000 The Rockefeller University Press. Creative Commons Attribution-NonCommercial-ShareAlike license

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