Xenbase Image ID: 23933

Figure 2. Fli1 Is Required Upstream of Gata2 for the Definitive Hemangioblast Program(A–L) Fli1 requirement for the definitive hemangioblast. Xenopus embryos injected with Fli1 MO in the VMZ at the 4-cell stage were processed for WISH at stage 26. Note remaining DLP signal in (B) marks the pronephric duct (PND). Red outlines hemangioblasts, black outlines PND. Black arrows, DLP; red arrows, pVBI.(M–T) Gata2 morphants confirm that Fli1 is at the top of the definitive hemangioblast hierarchy. Embryos injected with Gata2 MOs in the VMZ at the 4-cell stage were processed for WISH for expression in the DLP (arrows) at stages shown. Image published in: Liu F et al. (2008) Copyright © 2008. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue gata2 GATA-2, xGATA-2, xgata2 Xenopus Throughout unspecified stage fli1 fli, fli-1, fli1-a, Xfli, Xfli-1, Xfli1 Xenopus Throughout unspecified stage Image source: Published Larger Image Printer Friendly View

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