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XB-ART-19081
Cell Biol Int 1995 Nov 01;1911:895-901. doi: 10.1006/cbir.1995.1027.
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Retinoic acid induces changes in Xenopus embryo glycolipid pattern.

Rizzo AM, Gornati R, Rossi F, Bernardini G, Berra B.


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Retinoic acid (RA), known for its important role in cellular differentiation, may cause a modification of glycolipid distribution characterized by a shift from globoserie towards latto- and ganglio-series. In the present paper, we have investigated the modifications of the lipidic pattern after exogenous RA treatment of Xenopus embryos. We have noticed a decrease in neutral glycolipids with a parallel increase in gangliosides; the content of sulfatides does not seem to be modified. Beside the shift toward ganglio-serie, we have also observed a redistribution inside this class of lipids. In particular, following RA treatment, the relative distribution of GD1b and GT1b increases while that of GM3 decreases.

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