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Summary Literature (0)
DOID:5688 - Werner syndrome

Disease Ontology Definition:A progeroid syndrome characterized by premature aging and age-related phenotypes such as atherosclerosis, arteriosclerosis, cataracts, osteoporosis, soft tissue calcification, premature thinning, graying, and loss of hair, as well as a high incidence of some types of cancers and that has_material_basis_in mutations in the WRN gene, on chromosome 8.

Synonyms: adult premature ageing syndrome, adult progeria, Werner's syndrome, WS

Xenbase Genes : lmna, wrn

Mondo Disease Ontology (on Monarch Initiative):
MONDO:0010196 - Werner syndrome

MIM:
MIM:277700 - WERNER SYNDROME; WRN

Other Model Organisms: Alliance, MGI, ZFIN, FlyBase, WormBase, RGD

Ontology Viewers: Disease Ontology, EMBL-EBI, OLSVis tree view, Ontobee
Parent(s): autosomal recessive disease (is_a), progeroid syndrome (is_a), syndrome (is_a)