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XB-PHENO-23532

Xla Wt + adprhl1 CRISPR, Smith SJ et al. (2020)

Experiment + Assay: Xla Wt + adprhl1 CRISPR + NF33-39 (in situ)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR adprhl1 gRNA4 adprhl1 (Xla)
 NF stage 1 zygote
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 33 and 34 to NF stage 39  
Anatomical Phenotypes: abnormal development of cardiac ventricle , abnormal heart morphology
Expression Phenotypes (4):
mislocalised actc1.L expression in heart
decreased amount actc1.L expression in heart
mislocalised adprhl1.L expression in heart
decreased amount adprhl1.L expression in heart
Source: Fig. 6. CD
Article: XB-ART-57216, PubMed