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XB-PHENO-24214

Xla Wt + Hsa.DSPdel, Bharathan NK and Dickinson AJG (2019)

Experiment + Assay: Xla Wt + Hsa.DSPdel + NF26-28 (immunohistochemistry)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(Hsa.DSPdel) dsp (Xla)
 NF stage 1 zygote
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 26 to NF stage 28 Tuba4a Ab20
Anatomical Phenotypes: abnormal development of multiciliated cell, abnormally decreased number of multiciliated epidermal cell, abnormally localised multiciliated cell
Human Disease Associations: skin disease
Source: Fig. 7 F F'
Article: XB-ART-55821, PubMed