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XB-PHENO-25380

Xla Wt + pqbp1 MO, Iwasaki Y and Thomsen GH (2014)

Experiment + Assay: Xla Wt + pqbp1 MO + NF24 (whole-mount microscopy)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection pqbp1 MO2 pqbp1.S
 NF stage 2 (2-cell) blastomere
morpholino injection pqbp1 MO3 pqbp1.L
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
whole-mount microscopy NF stage 24  
Anatomical Phenotypes: abnormally increased number of apoptotic cell, absent tail bud, decreased length of anterior-posterior axis, decreased size of the head
Human Disease Associations: Renpenning syndrome
Source: Fig.2.F
Article: XB-ART-49433, PubMed