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XB-PHENO-25394

Xla Wt + pqbp1 MO + wbp11 MO, Iwasaki Y and Thomsen GH (2014)

Experiment + Assay: Xla Wt + pqbp1 MO + wbp11 MO + NF20 (whole-mount microscopy)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection pqbp1 MO3 pqbp1.L
 NF stage 3 (4-cell) blastomere
morpholino injection pqbp1 MO2 pqbp1.S
 NF stage 3 (4-cell) blastomere
morpholino injection wbp11 MO1 wbp11 (Xla)
 NF stage 3 (4-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
whole-mount microscopy NF stage 20  
Anatomical Phenotypes: abnormal incomplete closing of the blastopore, abnormally increased number of apoptotic cell, abnormal neural fold morphology
Source: Fig.4.D
Article: XB-ART-49433, PubMed