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XB-PHENO-25848

Xtr Wt + hif1a MO NF2, Patel JH et al. (2022)

Experiment + Assay: Xtr Wt + hif1a MO NF2 + NF18 (in situ hybridization)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection hif1a MO3 hif1a
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 18  
Anatomical Phenotypes: abnormal cranial neural crest morphology, decreased cell migration in branchial crest, decreased cell migration in cranial neural crest, decreased cell migration in hyoid crest, decreased cell migration in mandibular crest
Source: Fig. 5A
Article: XB-ART-58820, PubMed