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XB-PHENO-25899

Xtr WT + TALEN hps6, Nakayama T et al. (2017)

Experiment + Assay: Xtr WT + TALEN hps6 + NF46-47 (whole-mount microscopy)
Background: Xtr.Ivory CoastNXR
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
TALEN hps6
NF stage 1 whole organism
Conditions:
Assay Type Assay Stages Antibody
whole-mount microscopy NF stage 46 to NF stage 47  
Anatomical Phenotypes: abnormal eye morphology, abnormal inner ear morphology, abnormal intestine morphology, absent iridophore, decreased pigmentation in the epidermis, decreased pigmentation in the eye, decreased pigmentation in the whole organism, decreased size of the eye
Human Disease Associations: visceral heterotaxy, Hermansky-Pudlak syndrome
Source: Fig. 9 B: bcd; C:bcd; D:bc
Article: XB-ART-52468, PubMed