Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-PHENO-25910

Xla WT + ssbp2 MO, Cervino AS et al. (2023)

Experiment + Assay: Xla WT + ssbp2 MO + NF32 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection ssbp2 MO1 ssbp2 (Xla)
 NF stage 2 (2-cell) animal pole
lineage tracer ssbp2-eGFP mRNA
NF stage 2 (2-cell) animal pole
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 32  
Anatomical Phenotypes: abnormal pronephric tubule morphology , decreased size of the distal tubule , decreased size of the pronephric tubule , decreased size of the proximal tubule
Expression Phenotypes (4):
decreased amount clcnkb.L expression in pronephric tubule
decreased amount pax2.L expression in pronephric tubule
decreased amount pax2.L expression in proximal tubule
decreased amount slc5a1.L expression in proximal tubule
Source: Fig. 5 e, j, o
Article: XB-ART-60322, PubMed