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XB-PHENO-26025

Xla Wt + pax2 MO, Buisson I et al. (2015)

Experiment + Assay: Xla Wt + pax2 MO + NF33/34-35/36 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection pax2 MO2 pax2.L
pax2.S
NF stage 4 (8-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 33 and 34 to NF stage 35 and 36  
Expression Phenotypes (6):
decreased amount atp1b1.L expression in pronephric tubule
absent clcnkb.L expression in pronephric duct
absent clcnkb.L expression in pronephric kidney
decreased amount cldn19.L expression in proximal tubule
decreased amount slc12a1.L expression in proximal tubule
decreased amount slc4a4.L expression in proximal tubule
Source: Fig. 2 B, i-m
Article: XB-ART-49971, PubMed