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XB-PHENO-26040

Xla Wt + nav2 CRISPR, Weiss B et al. (2023)

Experiment + Assay: Xla Wt + nav2 CRISPR + NF45 (whole-mount microscopy)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR nav2 sgRNA1 nav2.L
nav2.S
 NF stage 1 whole organism
Conditions:
Assay Type Assay Stages Antibody
whole-mount microscopy NF stage 45  
Anatomical Phenotypes: abnormal cloaca morphology, abnormal head morphology, abnormal hindgut morphology, abnormally decreased coiling of small intestine, abnormal midgut morphology, decreased size of the main body axis, edematous head, edematous ventral trunk, increased size of the main body axis
Source: Fig. S2 BB'CDE
Article: XB-ART-60493, PubMed